| | Statistic | FOR | OPP |
| Total Yards per Game | 473.5 | 388.0 |
| Rushing YDS per ATT | 4.0 | 4.8 |
| Passing YDS per ATT | 7.5 | 6.9 |
| Passing Comp % | 0.614 | 0.559 |
| Total YDS per Play | 6.4 | 5.9 |
| Total YDS per Point | 16.3 | 12.3 |
|
| Injury |
| (!)[RB] 09/16/2018 - Le'Veon Bell is out indefinitely ( Holdout ) |
| [CB] 09/16/2018 - Joe Haden is "?" Monday vs Tampa Bay ( Hamstring ) |
| [G] 09/16/2018 - David DeCastro is "?" Monday vs Tampa Bay ( Hand ) |
| [DE] 09/16/2018 - Tyson Alualu is "?" Monday vs Tampa Bay ( Shoulder ) |
| [WR] 09/09/2018 - Eli Rogers PUP ( ACL ) |
| [TE] 09/04/2018 - Jake McGee IR ( Achilles ) |
| [LB] 09/04/2018 - Olasunkanmi Adeniyi IR ( Hamstring ) |
| [TE] 09/04/2018 - Ryan Malleck IR ( Undisclosed ) |
| [DB] 09/04/2018 - Trey Johnson IR ( Shoulder ) |
| [T] 08/03/2018 - Jerald Hawkins IR ( Quad ) |
| [LB] 08/03/2018 - Ryan Shazier IR ( Back ) |
