| | Statistic | FOR | OPP |
| Total Yards per Game | 377.9 | 373.1 |
| Rushing YDS per ATT | 5.5 | 5.3 |
| Passing YDS per ATT | 8.6 | 7.2 |
| Passing Comp % | 0.593 | 0.612 |
| Total YDS per Play | 7.3 | 6.5 |
| Total YDS per Point | 14.5 | 14.8 |
|
| Injury |
| [DB] Leron Mitchell out indefinitely - Fibula - 07/07/08 |
| [DL] Eddie Davis injured last game %27?%27 - Undisclosed - 09/28/08 |
| [DL] John Chick missed last game %27?%27 - Finger - 09/28/08 |
| [DT] Marcus Adams missed last game %27?%27 - Ankle - 09/28/08 |
| [FB] Neal Hughes is expected to miss at least a month. - Fibula - 08/05/08 |
| [lb] Anton McKenzie missed last game %27?%27 - Undisclosed - 09/29/08 |
| [LB] Brandon Lynch missed last game %27?%27 - Leg - 09/28/08 |
| [OL] Jeremy O'Day is out indefinitely. - Knee - 09/22/08 |
| [OL] Marc Parenteau missed last game %27?%27 - Knee - 09/28/08 |
| [OT] Belton Johnson missed last game %27?%27 - Fibula - 09/28/08 |
| [RB] Wes Cates missed last game %27?%27 - Calf - 09/28/08 |
| [SB] Andy Fantuz could miss up to 10 weeks. - Fibula - 07/29/08 |
| [WR] Adarius Bowman missed last game %27?%27 - Undisclosed - 09/29/08 |
| [WR] Carl Berman is expected to miss the rest of the season. - Achilles - |
| [WR] Chris Getzlaf IR - Undisclosed - 08/05/08 |
| [WR] D.J. Flick out indefinitely. - Fibula - 07/06/08 |
| [WR] David McKoy IR - Knee - 08/05/08 |
| [WR] Matt Dominguez is expected to miss the rest of the season. - Knee - 0 |
| [WR] T.J. Acree IR - Foot - 08/05/08 |