| | Statistic | FOR | OPP |
| Total Yards per Game | 295.5 | 296.5 |
| Rushing YDS per ATT | 4.1 | 3.1 |
| Passing YDS per ATT | 5.3 | 5.2 |
| Passing Comp % | 0.567 | 0.622 |
| Total YDS per Play | 4.7 | 4.1 |
| Total YDS per Point | 13.6 | 24.7 |
|
| Injury |
| [DT] 09/26/2021 - Bryan Bresee is out for season ( Knee ) |
| [LB] 09/25/2021 - Baylon Spector is "?" Saturday vs Boston College ( Undisclosed ) |
| [RB] 09/25/2021 - Will Shipley is out indefinitely ( Knee ) |
| [CB] 09/25/2021 - Fred Davis II is "?" Saturday vs Boston College ( Undisclosed ) |
| [RB] 09/20/2021 - Lyn-J Dixon is out for season ( Left Team ) |
| [DL] 09/20/2021 - Tyler Davis is out indefinitely ( Biceps ) |
| [DL] 09/15/2021 - Tayquon Johnson is out for season ( Pectoral ) |
| [OL] 09/14/2021 - Dietrick Pennington is out for season ( ACL ) |
| [S] 09/06/2021 - Lannden Zanders is out for season ( Shoulder ) |
| [WR] 09/02/2021 - Brannon Spector is out indefinitely ( COVID-19 ) |
