| | Statistic | FOR | OPP |
| Total Yards per Game | 377.9 | 349.9 |
| Rushing YDS per ATT | 4.8 | 4.8 |
| Passing YDS per ATT | 6.8 | 7.1 |
| Passing Comp % | 0.642 | 0.642 |
| Total YDS per Play | 5.8 | 6.0 |
| Total YDS per Point | 15.7 | 13.0 |
|
| Injury |
| [C] Ethan Pocic (Knee) - Out (Injured Reserve) [11/20/2022] => Pocic has been placed on injured reserve due to a knee injury and will miss at least 4 weeks. |
| [CB] Greg Newsome II (Head) - Out [11/18/2022] => Newsome has been ruled out heading into Week 12 versus the Buccaneers. |
| [G] Michael Dunn (Back) - Out (Injured Reserve) [11/16/2022] => Dunn has been placed on injured reserve due to a back injury and will miss at least four weeks. |
| [OT] Joe Haeg (Concussion) - Out (Injured Reserve) [10/29/2022] => Haeg has been placed on the injured reserve list due to a concussion and will miss at least four weeks. |
| [LB] Jacob Phillips (Pectoral) - Out (Injured Reserve) [10/23/2022] => Phillips has been placed on the injured reserve list due to a pectoral injury and wil miss at least four weeks. |
| [LB] Anthony Walker Jr. (Quad) - Out (Injured Reserve) [09/22/2022] => Walker Jr. has suffered a torn quad and will miss the remainder of the 2022 2023 season. |
| [TE] Jesse James (Biceps) - Out (Injured Reserve) [09/19/2022] => James is dealing with a bicep injury and has been placed on the Injured Reserve. He will miss at least 4 Weeks. |
| [LB] Chris Odom (Knee (ACL)) - Out (Injured Reserve) [08/28/2022] => Odom has been placed on the injured reserved list due to a torn ACL and will miss the remainder of the 2022-2023 season. |
| [G] Dawson Deaton (ACL) - Out (Injured Reserve) [08/15/2022] => Deaton has been placed on the injured reserve list due a torn ACL and will miss the 2022-2023 season. |
| [C] Nick Harris (Knee) - Out (Injured Reserve) [08/13/2022] => Harris has been placed on the injured reserve list due to a knee injury and will miss the 2022-2023 season. |
| [WR] Jakeem Grant Sr. (Achilles) - Out (Injured Reserve) [08/10/2022] => Grant has been placed on the injured reserve list due to a torn Achilles and will miss the 2022-2023 season. |
| [DE] Stephen Weatherly (Knee) - Out (Injured Reserve) [08/06/2022] => Weatherly has been placed on the injured reserve list due to a knee injury and will miss the 2022-2023 season. |
| [WR] Isaiah Weston (Knee) - Out (Injured Reserve) [08/02/2022] => Weston has been placed on the injured reserve list due to a meniscus injury and will miss the 2022-2023 season. |
| [QB] Deshaun Watson (Suspension) - Out (Suspended) [08/01/2022] => Watson has been suspended 11 regular season games for violating the NFL's personal conduct policy. He is eligible to return in Week 13 pending reinstatement by the league. |
